Zach McKinstry homered and drove in three runs, helping the Chicago Cubs beat the St. Louis Cardinals 7-1

Jose Altuve hit a leadoff homer and Trey Mancini added a two-run shot to back up another quality start by Framber Valdez, and the Houston Astros held on for a 5-3 win over the Minnesota Twins

Seattle right-hander George Kirby set a major league record by throwing 24 straight strikes to start the game and fellow Mariners rookie Julio Rodriguez reached a new level, but Ildemaro Vargas hit a two-run homer in the ninth inning that lifted the Washington Nationals to a 3-1 win

Rookie Oscar Gonzalez and Andrés Giménez homered off former Cleveland pitcher Mike Clevinger and the AL Central-leading Guardians beat the San Diego Padres 3-1